The quartet missed the Champions League semi-final exit to Atlético Madrid – Lampard and Mikel were suspended, Matic and Salah ineligible – while Ramires serves the second of his four-match ban.
Captain John Terry, Eden Hazard and Samuel Eto’o featured against Atlético despite recent injuries, while Oscar was on the bench, with all four fitness concerns and goalkeeper Petr Cech out.
Meanwhile, Norwich manager Neil Adams is hopeful of having defender Joseph Yobo at Stamford Bridge.
The on-loan Nigeria international has not played since Adams replaced Chris Hughton in March but is back in contention following a calf injury.
The trip to Stamford Bridge comes too soon for winger Anthony Pilkington (hip) as Adams looks to name a side that can give the Canaries the best chance of picking up an unlikely result to keep their survival prospects alive.
With the Champions League just a memory, Chelsea can now concentrate on the Premier League, knowing that they can go top with just one game to play with a victory.
And if Manchester City falter at Everton, the prospect of taking the title will improve.
Norwich’s future could be shaped at Stamford Bridge.
Their recent away form has been dreadful and another defeat will point them closer to the Championship.
Stat of the game: Norwich have lost their last eight away games in the Premier League.
Chelsea (Possible, 4-2-3-1): Schwarzer; Ivanovic, Cahill, Terry, Azpilicueta; Matic, Lampard; Oscar, Willian, Schürrle; Torres.
Out: Cech (shoulder), Ramires (suspended).
Tests: Terry (ankle), Hazard (calf), Eto’o (knee), Oscar (hip).
Norwich (Possible, 4-3-1-2): Ruddy; Whittaker, Martin, Yobo, Olsson; Johnson, Howson, Fer; Snodgrass; Van Wolfswinkel, Redmond.
Out: Pilkington (hip).
Test: Yobo (calf).
Referee: Neil Swarbrick. Matches: 19, R0 Y68.