Two-time winners France are hoping to match Germany and Spain – teams who represent their main rivals for glory this year – by winning a third continental title.
France come into the event in fine form having won nine of their last 10 matches after rounding off their preparation with a 3-0 win over Scotland last Saturday.
Deschamps has a key selection dilemma in attack after star striker Karim Benzema was not considered for selection due to an ongoing legal investigation into an alleged plot to blackmail fellow international Mathieu Valbuena.
Antoine Griezmann is almost certain to fill one of the three attacking positions, with Kingsley Coman, Andre-Pierre Gignac, Olivier Giroud, Anthony Martial and Dimitri Payet fighting over the other two spots.
Giroud has been receiving a negative reaction from some parts of the France support despite scoring seven goals in his last five starts, while Payet produced a trademark free-kick to seal victory over Cameroon on May 30 – form which perhaps gives that duo the edge.
“Griezmann is happy,” Deschamps said to L’Equipe ahead of the match. “He had a long season with Atletico and our main priority was to give him some rest before the start of the tournament.
“Antoine has certain qualities that make him one of the best attackers around in Europe. He has always been a good player, but he has become more consistent.
“He will be ready, but he will not necessarily be the leader of our attack. I have six attackers with a lot of quality and with different profiles.”
After Lassana Diarra’s injury, Leicester City’s N’Golo Kante is hoping to fill the final midfield spot alongside Blaise Matuidi and Paul Pogba, while Adil Rami appears to have won the race to partner Laurent Koscielny at centre-back with a number of key defenders – including Raphael Varane – out injured.
With France seen as the team to beat in the competition, Europe may be expecting a home victory against Romania, but the visitors are not to be underestimated despite having only ever won one of their 13 Euros matches, a result which came against England at Euro 2000.
Les Bleus may be unbeaten in 10 matches against Romania, but four of the last five meetings have ended in draws, while Anghel Iordanescu’s men had the best defensive record in qualifying – only conceding twice in 10 games.
The two nations have met twice before in the tournament’s group stages, with France winning 1-0 in 1996 and a 0-0 draw at Euro 2008.
Romania are not a squad of seasoned internationals, though. The visitors have the second least experienced squad at the tournament with their 23 players having an average of just 22.4 caps at the start of June.